Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183528 | 0.93 | KDM4E (0.48) | KDM4EALDH1A1TSHRL3MBTL1POLB | |
| SCHEMBL21458748 | 0.93 | BRD4 (0.40) | KDM4EALDH1A1TSHRHPGDBRD4 | |
| SCHEMBL20183682 | 0.91 | KDM4E (0.46) | KDM4EALDH1A1TSHRHPGDL3MBTL1 | |
| SCHEMBL20183878 | 0.91 | KDM4E (0.46) | KDM4EALDH1A1TSHRHPGDL3MBTL1 | |
| SCHEMBL20183621 | 0.90 | KDM4E (0.46) | KDM4EALDH1A1TSHRHPGDL3MBTL1 | |
| SCHEMBL20183623 | 0.89 | KDM4E (0.45) | KDM4EALDH1A1L3MBTL1POLBBRD4 | |
| SCHEMBL20183627 | 0.89 | CNR2 (0.44) | KDM4EBRD4MEN1KMT2AHSD17B10 | |
| SCHEMBL20183785 | 0.88 | KDM4E (0.43) | KDM4EALDH1A1L3MBTL1POLBBRD4 | |
| SCHEMBL20183700 | 0.88 | MEN1 (0.42) | KDM4EALDH1A1TSHRHPGDBRD4 | |
| SCHEMBL20183811 | 0.87 | ALDH1A1 (0.42) | KDM4EALDH1A1TSHRHPGDBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137505-B | Nitrogen-containing heterocyclic compound | 富士胶片株式会社 | 2021-07-06 | — | — | CN | disclosed |