Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.41 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885661 | 0.78 | MEN1 (0.51) | MEN1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL2627252 | 0.75 | MAP4K4 (0.60) | MEN1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL11780809 | 0.72 | MEN1 (0.56) | MEN1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL14320513 | 0.72 | CLK4 (0.46) | MEN1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL22655931 | 0.72 | PPM1B (0.43) | MEN1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL12171957 | 0.71 | MEN1 (0.64) | MEN1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL27775532 | 0.71 | KDM4E (0.47) | MEN1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL20745651 | 0.70 | SMN1; SMN2 (0.49) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL25458430 | 0.69 | SMN1; SMN2 (0.40) | MEN1KDM4EMAPTKMT2AMAP4K4 | |
| SCHEMBL22347249 | 0.69 | MECP2 (0.49) | MEN1ALDH1A1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195475-A | Inhibitors of human immunodeficiency virus replication | VIIV保健英国第五有限公司 | 2021-07-30 | — | — | CN | disclosed |