Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.44 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28617164 | 1.00 | PLA2G10 (0.44) | PLA2G10PLA2G5ALDH1A1KDM4ECASP3 | |
| SCHEMBL30191344 | 1.00 | PLA2G10 (0.44) | PLA2G10PLA2G5ALDH1A1KDM4ECASP3 | |
| SCHEMBL30191487 | 0.78 | PLA2G10 (0.44) | PLA2G10PLA2G5ALDH1A1KDM4E | |
| SCHEMBL28607923 | 0.77 | PLA2G10 (0.46) | PLA2G10PLA2G5ALDH1A1KDM4E | |
| SCHEMBL28607924 | 0.77 | PLA2G10 (0.46) | PLA2G10PLA2G5ALDH1A1KDM4E | |
| SCHEMBL24714971 | 0.76 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL15485386 | 0.72 | BRD4 (0.43) | ALDH1A1KDM4EKMT2ATP53 | |
| SCHEMBL11327841 | 0.71 | HPGD (0.58) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL21995001 | 0.71 | PLA2G10 (0.44) | PLA2G10PLA2G5ALDH1A1KDM4ECASP3 | |
| SCHEMBL19674208 | 0.70 | HSD17B10 (0.40) | ALDH1A1KDM4EMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166101-A | Cyclic pentameric compounds as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for the treatment of metabolic disorders | 诺华股份有限公司 | 2021-07-23 | — | — | CN | disclosed |