Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523188 | 0.88 | KDM4E (0.63) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4728062 | 0.88 | KDM4E (0.63) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30523189 | 0.88 | KDM4E (0.63) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4287532 | 0.82 | CYP2D6 (0.52) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL31078487 | 0.82 | CYP2D6 (0.52) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL19161142 | 0.81 | KDM4E (1.00) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1491505 | 0.81 | KDM4E (1.00) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1491317 | 0.81 | KDM4E (1.00) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1491315 | 0.81 | KDM4E (1.00) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL31374991 | 0.80 | KDM4E (0.97) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121527-B | Tricyclic compounds and uses thereof | 上海辉启生物医药科技有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-113121527-A | Tricyclic compound and use thereof | 上海辉启生物医药科技有限公司 | 2021-07-16 | — | — | CN | disclosed |