Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.56 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523189 | 1.00 | KDM4E (0.63) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL30523188 | 1.00 | KDM4E (0.63) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL28617486 | 0.88 | KDM4E (0.67) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL4727252 | 0.86 | KDM4E (0.64) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL31078247 | 0.86 | KDM4E (0.64) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL2309545 | 0.83 | NR2E1 (0.60) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL31078488 | 0.83 | NR2E1 (0.64) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL31078875 | 0.83 | NR2E1 (0.60) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL4903024 | 0.83 | NR2E1 (0.64) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL12660565 | 0.83 | NR2E1 (0.60) | KDM4EHSD17B10ALDH1A1CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396278-A | Carbazole derivatives as dopamine D3 receptor selectivity modulators | 北京大学 | 2023-07-07 | — | — | CN | disclosed |
| CN-113121527-A | Tricyclic compound and use thereof | 上海辉启生物医药科技有限公司 | 2021-07-16 | — | — | CN | disclosed |
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |