Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | HPN | P05981 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 5/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 4/20 | 0.40 |
| ▸ | NPR3 | P17342 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28617672 | 1.00 | S1PR1 (0.46) | S1PR1AAK1PLAUHPNIDO1 | |
| SCHEMBL28604846 | 1.00 | S1PR1 (0.46) | S1PR1AAK1PLAUHPNIDO1 | |
| SCHEMBL28603117 | 0.85 | AAK1 (0.44) | AAK1PLAUHPNFPR2MMP13 | |
| SCHEMBL28603119 | 0.85 | AAK1 (0.44) | AAK1PLAUHPNFPR2MMP13 | |
| SCHEMBL22143981 | 0.85 | AAK1 (0.44) | AAK1PLAUHPNFPR2MMP13 | |
| SCHEMBL24593528 | 0.85 | AAK1 (0.44) | AAK1PLAUHPNFPR2MMP13 | |
| SCHEMBL28606581 | 0.84 | AAK1 (0.44) | AAK1PLAUHPNFPR2MMP13 | |
| SCHEMBL28614617 | 0.83 | GPR119 (0.45) | AAK1PLAUHPNIDO1FPR2 | |
| SCHEMBL28604647 | 0.82 | GPR119 (0.46) | AAK1PLAUHPNIDO1FPR2 | |
| SCHEMBL28604646 | 0.82 | GPR119 (0.46) | AAK1PLAUHPNIDO1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164448-A | Amino acid anilines as small molecule modulators of IL-17 | 利奥制药有限公司 | 2021-07-23 | — | — | CN | disclosed |