Crotonic Acid

Crotonic Acid

SCHEMBL28618133

C/C=C/C(=O)O.O=C1CCCCCO1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.55
CA9 Q16790 1/20 0.55
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 3/20 0.32
INMT O95050 2/20 0.32
CYP1A2 P05177 1/20 0.32
PGR P06401 2/20 0.31
FKBP4 Q02790 3/20 0.31
POLB P06746 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Crotonic Acid SCHEMBL27977237 0.93 CA1 (0.48) CA1CA9ALDH1A1LMNATP53
Fumaric Acid SCHEMBL30153854 0.89 CA1 (0.64) CA1CA9ALDH1A1LMNATP53
Maleic Acid SCHEMBL5166062 0.89 CA1 (0.64) CA1CA9ALDH1A1LMNATP53
Fumaric Acid SCHEMBL301635 0.89 CA1 (0.64) CA1CA9ALDH1A1LMNATP53
Crotonic Acid SCHEMBL28035350 0.86 CA1 (0.41) CA1CA9
SCHEMBL18045659 0.84 CA1 (0.57) CA1CA9ALDH1A1LMNATP53
SCHEMBL28227337 0.83 CA1 (0.73) CA1CA9ALDH1A1LMNATP53
Bicarbonate SCHEMBL27877696 0.82 CA1 (0.59) CA1CA9ALDH1A1LMNATP53
Acetic Acid SCHEMBL27560595 0.81 CA1 (0.70) CA1CA9ALDH1A1LMNATP53
Bicarbonate SCHEMBL8606312 0.81 CA1 (0.76) CA1CA9ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113087836-B Oil field pour point depressant and preparation method thereof 中海油(天津)油田化工有限公司 2022-10-04 CN claimed
CN-113087836-B Oil field pour point depressant and preparation method thereof 中海油(天津)油田化工有限公司 2022-10-04 CN disclosed
CN-114672295-A Crude oil wax-proof pour point depressant and preparation method thereof 中海油(天津)油田化工有限公司 2022-06-28 CN disclosed
CN-113087836-A Oil field pour point depressant and preparation method thereof 中海油(天津)油田化工有限公司 2021-07-09 CN disclosed