Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606605 | 0.83 | HDAC1 (0.57) | PTGDR2CYP2C9CREBBPHDAC6HDAC10 | |
| SCHEMBL28473909 | 0.82 | CYP1A2 (0.62) | PTGDR2CYP2C9HTR5AHDAC6HDAC10 | |
| SCHEMBL28607599 | 0.81 | PTGDR2 (0.62) | PTGDR2CYP2C9PTGER2PTGDRHDAC6 | |
| SCHEMBL19132555 | 0.79 | PTGDR2 (0.66) | PTGDR2CYP2C9PTGER2PTGDRHTR5A | |
| SCHEMBL28614904 | 0.79 | HDAC6 (0.56) | PTGDR2CYP2C9PTGER2PTGDRHDAC6 | |
| SCHEMBL28607187 | 0.78 | PTGDR2 (0.52) | PTGDR2CYP2C9PTGER2PTGDRCREBBP | |
| SCHEMBL28609619 | 0.74 | PTGDR2 (0.48) | PTGDR2CYP2C9PTGER2PTGDRHTR5A | |
| SCHEMBL2246361 | 0.74 | PTGDR2 (0.66) | PTGDR2CYP2C9PTGER2PTGDRHDAC6 | |
| SCHEMBL2247025 | 0.74 | PTGDR2 (0.60) | PTGDR2CYP2C9PTGER2PTGDRHTR5A | |
| SCHEMBL969366 | 0.74 | HTR5A (0.52) | PTGDR2HTR5AHDAC6HDAC10HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121527-A | Tricyclic compound and use thereof | 上海辉启生物医药科技有限公司 | 2021-07-16 | — | — | CN | disclosed |