Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | FABP3 | P05413 | 3/20 | 0.40 |
| ▸ | FABP4 | P15090 | 3/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL25170761 | 0.92 | TSHR (0.53) | TSHRALDH1A1KMT2AHPGDKDM4E | |
| SCHEMBL73044 | 0.90 | TSHR (0.59) | TSHRALDH1A1KMT2AHPGDKDM4E | |
| SCHEMBL28022554 | 0.88 | TSHR (0.57) | TSHRALDH1A1KMT2AHPGDKDM4E | |
| SCHEMBL28079050 | 0.88 | TSHR (0.57) | TSHRALDH1A1KMT2AHPGDKDM4E | |
| Lithium Ion SCHEMBL31615963 | 0.86 | TSHR (0.47) | TSHRALDH1A1KMT2AHPGDKDM4E | |
| SCHEMBL31616011 | 0.83 | TSHR (0.47) | TSHRALDH1A1KMT2AHPGDKDM4E | |
| Lithium Ion SCHEMBL28608653 | 0.83 | ALDH1A1 (0.41) | TSHRALDH1A1KMT2AHPGDKDM4E | |
| Lithium Ion SCHEMBL28608649 | 0.83 | ALDH1A1 (0.41) | TSHRALDH1A1KMT2AHPGDKDM4E | |
| Lithium Ion SCHEMBL28703021 | 0.80 | KMT2A (0.46) | TSHRALDH1A1KMT2AHPGDKDM4E | |
| SCHEMBL31615858 | 0.79 | ALDH1A1 (0.41) | TSHRALDH1A1KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107431245-B | Nonaqueous electrolyte solution for secondary battery and secondary battery provided with same | 斯泰拉化工公司 | 2021-08-10 | — | — | CN | disclosed |