Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28608791 | 0.88 | HTT (0.47) | ADAM17GAA | |
| SCHEMBL26673483 | 0.85 | F2 (0.45) | F2F10ADAM17ALDH1A1KMT2A | |
| SCHEMBL28618856 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1USP2GAA | |
| SCHEMBL28618855 | 0.82 | MAPT (0.46) | ADAM17ALDH1A1CA1CA2CA4 | |
| SCHEMBL29720620 | 0.79 | F10 (0.41) | F2F10CA1CA2CA4 | |
| SCHEMBL26673511 | 0.79 | F10 (0.45) | F2F10ALDH1A1USP2GAA | |
| SCHEMBL30608846 | 0.79 | F10 (0.45) | F2F10ALDH1A1USP2GAA | |
| SCHEMBL26673510 | 0.79 | F2 (0.48) | F2F10ADAM17ALDH1A1CA1 | |
| SCHEMBL26673488 | 0.77 | ALDH1A1 (0.53) | F2F10ADAM17ALDH1A1KMT2A | |
| SCHEMBL28601239 | 0.77 | HTT (0.49) | ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113105395-B | 4-phenylsulfonyl-1-trihydroxy benzoyl piperazine-2-carboxamide derivative and preparation method and application thereof | 山东大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-113105395-A | 4-phenylsulfonyl-1-trihydroxy benzoyl piperazine-2-carboxamide derivative and preparation method and application thereof | 山东大学 | 2021-07-13 | — | — | CN | disclosed |