Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210779 | 0.87 | BACE1 (0.42) | BACE1HSD11B1 | |
| SCHEMBL8196623 | 0.87 | CHRNA1 (0.43) | BACE1 | |
| SCHEMBL4559993 | 0.85 | PGR (0.40) | BACE1 | |
| SCHEMBL7601377 | 0.83 | BACE1 (0.34) | BACE1MGAT2 | |
| SCHEMBL7536095 | 0.82 | BACE1 (0.42) | BACE1HSD11B1 | |
| SCHEMBL2969215 | 0.82 | BACE1 (0.48) | BACE1 | |
| SCHEMBL2969213 | 0.82 | BACE1 (0.48) | BACE1 | |
| SCHEMBL7575214 | 0.82 | BACE1 (0.49) | BACE1HTR7 | |
| SCHEMBL7536384 | 0.81 | BACE1 (0.47) | BACE1 | |
| SCHEMBL13663871 | 0.81 | BACE1 (0.39) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290860-B | Iminotetrahydropyrimidinone derivatives as PLASMEPSIN V inhibitors | UCB生物制药有限责任公司 | 2021-08-10 | — | — | CN | disclosed |