Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RET | P07949 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28613370 | 0.86 | KDM1A (0.49) | ALDH1A1L3MBTL1TDP1KDM1AHTT | |
| SCHEMBL7689595 | 0.74 | KDM1A (0.57) | ALDH1A1KDM1AKDM4EKMT2AMEN1 | |
| SCHEMBL28609922 | 0.74 | KMT2A (0.57) | ALDH1A1L3MBTL1TDP1MAPK1HTT | |
| SCHEMBL30437010 | 0.72 | KMT2A (0.61) | ALDH1A1TDP1MAPK1HTTKDM4E | |
| SCHEMBL30435875 | 0.71 | SMN1; SMN2 (0.45) | ALDH1A1L3MBTL1TDP1KDM1AHTT | |
| SCHEMBL30437291 | 0.71 | KDM4E (0.48) | ALDH1A1L3MBTL1TDP1MAPK1KDM1A | |
| SCHEMBL7845566 | 0.69 | KDM1A (0.47) | ALDH1A1KDM1AHPGDKDM4EMAPT | |
| SCHEMBL7999923 | 0.68 | KDM1A (0.49) | ALDH1A1L3MBTL1TDP1MAPK1KDM1A | |
| SCHEMBL902770 | 0.67 | KDM1A (1.00) | L3MBTL1TDP1MAPK1KDM1AHTT | |
| SCHEMBL20261927 | 0.67 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1TDP1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135852-B | Preparation method of 4-aminoquinoline compound | 中国科学院长春应用化学研究所 | 2023-06-20 | — | — | CN | disclosed |
| CN-113135852-A | Preparation method of 4-aminoquinoline compound | 中国科学院长春应用化学研究所 | 2021-07-20 | — | — | CN | disclosed |