Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18171353 | 0.86 | KDM4E (0.54) | KDM4EGAALMNAP4HTMNAPRT | |
| SCHEMBL22095471 | 0.79 | KDM4E (0.44) | KDM4EGAALMNANAPRTKMT2A | |
| SCHEMBL1217437 | 0.77 | KDM4E (1.00) | KDM4EGAALMNAP4HTMNAPRT | |
| SCHEMBL145208 | 0.77 | KDM4E (0.91) | KDM4EGAALMNAP4HTMNAPRT | |
| SCHEMBL28516172 | 0.77 | KDM4E (0.80) | KDM4EGAALMNAP4HTMNAPRT | |
| SCHEMBL1400875 | 0.77 | — | — | |
| SCHEMBL5471362 | 0.76 | KDM4E (0.87) | KDM4EGAALMNAP4HTMNAPRT | |
| Hydrochloric Acid SCHEMBL22440642 | 0.76 | KDM4E (0.87) | KDM4EGAALMNAP4HTMNAPRT | |
| SCHEMBL31114652 | 0.76 | KDM4E (0.95) | KDM4EGAALMNAP4HTMNAPRT | |
| SCHEMBL29096264 | 0.76 | KDM4E (0.87) | KDM4EGAALMNAP4HTMNAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218227-B | Method for preparing aryl ketone derivative | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |
| CN-110294776-B | Method for preparing aryl phosphine oxide derivative | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |
| CN-110229188-B | Preparation method of arylmethylphosphonic acid compound | 苏州大学 | 2021-08-27 | — | — | CN | disclosed |