Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28630911 | 0.80 | NPC1 (0.60) | ALDH1A1HTTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL28630208 | 0.78 | NPC1 (0.61) | HTTKDM4ESMN1; SMN2NPC1POLB | |
| SCHEMBL28615473 | 0.77 | NPC1 (0.60) | ALDH1A1HTTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL30039534 | 0.76 | NR1H4 (0.57) | ALDH1A1HTTNR1H4KDM4EGAA | |
| SCHEMBL28620514 | 0.76 | NPC1 (0.59) | ALDH1A1HTTKDM4EGAASMN1; SMN2 | |
| SCHEMBL28616235 | 0.76 | KDM4E (0.58) | ALDH1A1HTTKDM4EGAASMN1; SMN2 | |
| SCHEMBL28619420 | 0.75 | GAA (0.51) | ALDH1A1HTTNR1H4KDM4EGAA | |
| SCHEMBL28627525 | 0.75 | RAB9A (0.54) | HTTNR1H4KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL28373241 | 0.73 | NR1H4 (0.56) | ALDH1A1HTTNR1H4KDM4EGAA | |
| SCHEMBL28373238 | 0.72 | NR1H4 (0.55) | ALDH1A1HTTNR1H4KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372346-B | Synthetic method of 3-fatty amine methyl imidazo [1, 2-alpha ] pyridine compound | 南华大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-113372346-A | Synthetic method of 3-fatty amine methyl imidazo [1, 2-alpha ] pyridine compound | 南华大学 | 2021-09-10 | — | — | CN | disclosed |