Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28620837 | 0.90 | CYP2C9 (0.71) | CYP2C9RAB9AKMT2ASMN1; SMN2DNM1 | |
| SCHEMBL8952107 | 0.86 | CYP2C9 (1.00) | CYP2C9RAB9AKMT2ASMN1; SMN2PTP4A1 | |
| SCHEMBL29924198 | 0.86 | CYP2C9 (1.00) | CYP2C9RAB9AKMT2ASMN1; SMN2PTP4A1 | |
| SCHEMBL8952104 | 0.86 | CYP2C9 (1.00) | CYP2C9RAB9AKMT2ASMN1; SMN2PTP4A1 | |
| SCHEMBL23941236 | 0.83 | CYP2C9 (0.50) | CYP2C9RAB9AKMT2ASMN1; SMN2DNM1 | |
| SCHEMBL28852642 | 0.83 | CYP2C9 (0.50) | CYP2C9RAB9AKMT2ASMN1; SMN2DNM1 | |
| SCHEMBL24755221 | 0.79 | CYP2C9 (0.46) | CYP2C9RAB9AKMT2ASMN1; SMN2DNM1 | |
| SCHEMBL27638684 | 0.79 | CYP2C9 (0.46) | CYP2C9RAB9AKMT2ASMN1; SMN2DNM1 | |
| SCHEMBL8559723 | 0.78 | CYP2C9 (0.68) | CYP2C9RAB9AKMT2ASMN1; SMN2DNM1 | |
| SCHEMBL8559725 | 0.78 | CYP2C9 (0.68) | CYP2C9RAB9AKMT2ASMN1; SMN2DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135857-A | Synthesis method of N-hydroxyethyl-5-amino-1H pyrazole | 杭州迪克科技有限公司 | 2021-07-20 | — | — | CN | disclosed |