Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | PTP4A1 | Q93096 | 3/20 | 0.48 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.48 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559725 | 1.00 | CYP2C9 (0.68) | CYP2C9PTP4A1PTP4A3PTP4A2RAB9A | |
| SCHEMBL8952104 | 0.81 | CYP2C9 (1.00) | CYP2C9PTP4A1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL8952107 | 0.81 | CYP2C9 (1.00) | CYP2C9PTP4A1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL29924198 | 0.81 | CYP2C9 (1.00) | CYP2C9PTP4A1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL6293723 | 0.79 | PTP4A1 (0.49) | CYP2C9PTP4A1PTP4A3PTP4A2RAB9A | |
| SCHEMBL28619646 | 0.78 | CYP2C9 (0.75) | CYP2C9PTP4A1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL541316 | 0.78 | PTP4A1 (0.46) | CYP2C9PTP4A1PTP4A3PTP4A2RAB9A | |
| SCHEMBL7117452 | 0.77 | PTP4A3 (0.48) | CYP2C9PTP4A1PTP4A3PTP4A2RAB9A | |
| SCHEMBL7117459 | 0.77 | PTP4A3 (0.48) | CYP2C9PTP4A1PTP4A3PTP4A2RAB9A | |
| SCHEMBL28620837 | 0.75 | CYP2C9 (0.71) | CYP2C9PTP4A1RAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939424-A | ANTILIPEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-08-17 | — | — | US | disclosed |