Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16523540 | 0.93 | CYP3A4 (0.51) | CYP3A4ALDH1A1LMNAMAPTGAA | |
| SCHEMBL25546732 | 0.84 | CYP3A4 (0.58) | CYP3A4ALDH1A1LMNAMAPTGAA | |
| SCHEMBL1608218 | 0.84 | CYP3A4 (0.53) | CYP3A4ALDH1A1LMNAMAPTGAA | |
| SCHEMBL26773970 | 0.81 | ALDH1A1 (0.44) | CYP3A4ALDH1A1LMNAMAPTGAA | |
| SCHEMBL19509223 | 0.81 | CYP3A4 (0.50) | CYP3A4ALDH1A1LMNAMAPTGAA | |
| SCHEMBL26767234 | 0.78 | ALDH1A1 (0.44) | CYP3A4ALDH1A1LMNAMAPTGAA | |
| SCHEMBL26773942 | 0.78 | ALDH1A1 (0.44) | CYP3A4ALDH1A1LMNAMAPTGAA | |
| SCHEMBL24822836 | 0.78 | CYP3A4 (0.51) | CYP3A4ALDH1A1LMNAMAPTGAA | |
| SCHEMBL32666728 | 0.78 | CYP3A4 (0.47) | CYP3A4ALDH1A1LMNAMAPTGAA | |
| SCHEMBL27094979 | 0.78 | CYP3A4 (0.47) | CYP3A4ALDH1A1LMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113234079-B | Nucleoside analogs as PRMT5 inhibitors | 上海湃隆生物科技有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113234079-A | Nucleoside analogs as PRMT5 inhibitors | 上海湃隆生物科技有限公司 | 2021-08-10 | — | — | CN | disclosed |