Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365462 | 0.83 | MEN1 (0.49) | G6PDCASP7CASP6HTTKMT2A | |
| SCHEMBL27864020 | 0.80 | HTT (0.51) | G6PDCASP7CASP6HTTKMT2A | |
| SCHEMBL27412787 | 0.80 | HTT (0.51) | G6PDCASP7CASP6HTTKMT2A | |
| SCHEMBL27483873 | 0.80 | HTT (0.51) | G6PDCASP7CASP6HTTKMT2A | |
| SCHEMBL27633055 | 0.80 | HTT (0.51) | G6PDCASP7CASP6HTTKMT2A | |
| SCHEMBL28415093 | 0.80 | HTT (0.51) | G6PDCASP7CASP6HTTKMT2A | |
| SCHEMBL28415272 | 0.80 | HTT (0.51) | G6PDCASP7CASP6HTTKMT2A | |
| SCHEMBL11658216 | 0.80 | HTT (0.51) | G6PDCASP7CASP6HTTKMT2A | |
| Methoxymethane SCHEMBL5903652 | 0.78 | G6PD (0.63) | G6PDCASP7CASP6HTTMAPK1 | |
| SCHEMBL17799521 | 0.77 | G6PD (0.46) | G6PDCASP7CASP6MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292539-A | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-108026072-B | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2021-08-17 | — | — | CN | disclosed |