Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30323614 | 1.00 | NR1H2 (0.48) | NR1H2NR1H3RIPK1ACHERORC | |
| SCHEMBL27626911 | 0.84 | NR1H2 (0.49) | NR1H2 | |
| SCHEMBL13246586 | 0.79 | NR1H2 (0.47) | NR1H2NR1H3 | |
| SCHEMBL14038174 | 0.79 | NR1H2 (0.39) | NR1H2KDR | |
| SCHEMBL6846578 | 0.78 | NR1H2 (0.51) | NR1H2 | |
| SCHEMBL26613362 | 0.77 | RIPK1 (0.45) | RIPK1GPR119 | |
| SCHEMBL29746522 | 0.77 | RIPK1 (0.45) | RIPK1GPR119 | |
| SCHEMBL27681563 | 0.77 | NR1H2 (0.48) | NR1H2NR1H3 | |
| SCHEMBL10061592 | 0.76 | RIPK1 (0.61) | NR1H2NR1H3RIPK1ACHERORC | |
| SCHEMBL248353 | 0.76 | RIPK1 (0.61) | NR1H2NR1H3RIPK1ACHERORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |
| CN-112654608-A | Condensed ring compounds having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2021-04-13 | — | — | CN | disclosed |