Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 5/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 4/20 | 0.33 |
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6119785 | 1.00 | POLB (0.41) | POLBL3MBTL1RAB9ADPP4DPP8 | |
| SCHEMBL18458207 | 0.83 | RAB9A (0.41) | POLBL3MBTL1RAB9ADPP4DPP8 | |
| SCHEMBL12069452 | 0.80 | RAB9A (0.38) | POLBL3MBTL1RAB9ADPP4DPP8 | |
| SCHEMBL18015118 | 0.79 | ALOX5AP (0.45) | L3MBTL1HSD17B10 | |
| SCHEMBL18015115 | 0.79 | ALOX5AP (0.45) | L3MBTL1HSD17B10 | |
| SCHEMBL18015133 | 0.79 | ALOX5AP (0.45) | L3MBTL1HSD17B10 | |
| SCHEMBL13740550 | 0.79 | POLB (0.46) | POLBL3MBTL1RAB9ADPP4DPP7 | |
| SCHEMBL15608178 | 0.79 | POLB (0.46) | POLBL3MBTL1RAB9ADPP4DPP7 | |
| SCHEMBL3182268 | 0.77 | POLB (0.44) | POLBL3MBTL1RAB9ADPP4DPP8 | |
| SCHEMBL16612137 | 0.77 | POLB (0.44) | POLBL3MBTL1RAB9ADPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072542-A | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |