Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | NNMT | P40261 | 16/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18297461 | 0.84 | NNMT (0.35) | NNMTPRMT5WDR77 | |
| SCHEMBL30940848 | 0.84 | NNMT (0.35) | NNMTPRMT5WDR77 | |
| SCHEMBL30941131 | 0.82 | NNMT (0.39) | NNMTPRMT5WDR77 | |
| SCHEMBL31123819 | 0.82 | NNMT (0.40) | NNMTPRMT5WDR77 | |
| SCHEMBL17536694 | 0.82 | NNMT (0.38) | NNMTPRMT5WDR77 | |
| SCHEMBL23776516 | 0.82 | NNMT (0.39) | NNMTPRMT5WDR77 | |
| SCHEMBL20434796 | 0.82 | NNMT (0.40) | NNMTPRMT5WDR77 | |
| SCHEMBL31228243 | 0.82 | NNMT (0.38) | NNMTPRMT5WDR77 | |
| SCHEMBL18572583 | 0.82 | NNMT (0.40) | NNMTPRMT5WDR77 | |
| SCHEMBL19684630 | 0.82 | NNMT (0.40) | NNMTPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113234079-B | Nucleoside analogs as PRMT5 inhibitors | 上海湃隆生物科技有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113234079-A | Nucleoside analogs as PRMT5 inhibitors | 上海湃隆生物科技有限公司 | 2021-08-10 | — | — | CN | disclosed |