Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17522468 | 0.91 | KMT2A (0.47) | PROKR1KMT2ADAOMCL1MEN1 | |
| SCHEMBL13197458 | 0.85 | PROKR1 (0.42) | PROKR1KMT2ADAOMCL1MEN1 | |
| SCHEMBL16760322 | 0.82 | PROKR1 (0.44) | PROKR1CHRM1 | |
| SCHEMBL28201861 | 0.80 | PROKR1 (0.39) | PROKR1KMT2ADAOMCL1MEN1 | |
| SCHEMBL1460157 | 0.79 | MEN1 (0.36) | PROKR1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8248877 | 0.79 | NR1I2 (0.36) | PROKR1KMT2ATLR7MEN1KDM4E | |
| SCHEMBL8207552 | 0.79 | PROKR1 (0.41) | PROKR1KMT2ACHRM1ADRA1A | |
| SCHEMBL29188510 | 0.77 | LCK (0.35) | PROKR1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8242876 | 0.77 | ALDH1A1 (0.45) | KDM4EALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL13425054 | 0.76 | DRD1 (0.38) | ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402553-B | Phosphine ligand of 2-alkyl-indole skeleton, preparation method and application thereof | 香港理工大学深圳研究院 | 2023-06-16 | — | — | CN | disclosed |
| CN-113402553-A | 2-alkyl-indole skeleton phosphine ligand and preparation method and application thereof | 香港理工大学深圳研究院 | 2021-09-17 | — | — | CN | disclosed |