Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31441165 | 1.00 | AKT1 (0.44) | AKT1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL23113657 | 0.93 | AKT1 (0.46) | AKT1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL31374693 | 0.90 | NAMPT (0.42) | AKT1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL22207315 | 0.89 | FNTA (0.50) | AKT1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL22207314 | 0.89 | FNTA (0.50) | AKT1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL31441166 | 0.87 | FOLH1 (0.42) | AKT1MAPTMEN1KMT2ANPSR1 | |
| Trifluoroacetic Acid SCHEMBL31441171 | 0.86 | AKT1 (0.44) | AKT1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL22207235 | 0.85 | AKT1 (0.45) | AKT1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL22207234 | 0.85 | AKT1 (0.45) | AKT1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL23113658 | 0.85 | AKT1 (0.40) | AKT1MEN1KMT2ANAMPTGLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301920-A | Complexes comprising ligands, spacers, peptide linkers and biomolecules | 安斯泰来制药株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-113271973-A | Complex comprising a ligand and a CEACAM5 antibody Fab fragment | 安斯泰来制药株式会社 | 2021-08-17 | — | — | CN | disclosed |
| CN-112135841-A | Complexes comprising anti-human MUC1 antibody Fab fragments, peptide linkers, and/or ligands | 安斯泰来制药株式会社 | 2020-12-25 | — | — | CN | disclosed |