Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.50 |
| ▸ | FNTB | P49356 | 10/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22207314 | 1.00 | FNTA (0.50) | FNTAFNTBPGGT1BAKT1MAPT | |
| SCHEMBL28619772 | 0.92 | FNTA (0.46) | FNTAFNTBPGGT1BAKT1CA2 | |
| SCHEMBL28620704 | 0.89 | AKT1 (0.44) | FNTAFNTBAKT1MAPTMEN1 | |
| SCHEMBL31441165 | 0.89 | AKT1 (0.44) | FNTAFNTBAKT1MAPTMEN1 | |
| SCHEMBL28625037 | 0.86 | CTSS (0.48) | AKT1MAPTPOLBKDM4ECA2 | |
| SCHEMBL29460407 | 0.85 | FNTA (0.57) | FNTAFNTBMAPTMEN1KMT2A | |
| SCHEMBL23113657 | 0.83 | AKT1 (0.46) | FNTAFNTBPGGT1BAKT1MAPT | |
| SCHEMBL28627410 | 0.82 | FNTA (0.45) | FNTAFNTBPGGT1BAKT1MAPT | |
| SCHEMBL24312162 | 0.82 | FNTA (0.46) | FNTAFNTBPGGT1B | |
| SCHEMBL28620698 | 0.81 | FNTA (0.53) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301920-A | Complexes comprising ligands, spacers, peptide linkers and biomolecules | 安斯泰来制药株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-113271973-A | Complex comprising a ligand and a CEACAM5 antibody Fab fragment | 安斯泰来制药株式会社 | 2021-08-17 | — | — | CN | disclosed |
| WO-2020145227-A1 | COMPLEX COMPRISING LIGAND, SPACER, PEPTIDE LINKER, AND BIOMOLECULE | アステラス製薬株式会社 | 2020-07-16 | — | — | WO | disclosed |
| WO-2020145228-A1 | COMPLEX COMPRISING LIGAND AND CEACAM5 ANTIBODY FAB FRAGMENT | アステラス製薬株式会社 | 2020-07-16 | — | — | WO | disclosed |