SCHEMBL28620737

SCHEMBL28620737

O=C(O)c1cc(O)c(C(=O)O)c(S)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.46
SELL P14151 2/20 0.43
SELP P16109 2/20 0.43
CYP3A4 P08684 3/20 0.39
AKR1C4 P17516 2/20 0.39
AKR1C3 P42330 2/20 0.39
AKR1C2 P52895 2/20 0.39
AKR1C1 Q04828 2/20 0.39
ACHE P22303 1/20 0.39
MEN1 O00255 2/20 0.38
KDR P35968 2/20 0.38
KMT2A Q03164 2/20 0.38
PDE4A P27815 1/20 0.38
BLVRB P30043 1/20 0.38
HTT P42858 1/20 0.38
CA1 P00915 6/20 0.38
CA2 P00918 6/20 0.38
ALDH1A1 P00352 6/20 0.38
CA12 O43570 5/20 0.38
CA7 P43166 5/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL471902 0.85 THRB (0.50) THRBSELLSELPCYP3A4AKR1C4
SCHEMBL28062216 0.80 THRB (0.50) THRBSELLSELPCYP3A4AKR1C4
SCHEMBL28062166 0.76 THRB (0.45) THRBSELLSELPCYP3A4AKR1C4
SCHEMBL6902975 0.76 THRB (0.50) THRBSELLSELPCYP3A4AKR1C4
SCHEMBL31405600 0.75 CYP3A4 (0.48) THRBSELLSELPCYP3A4AKR1C4
SCHEMBL3517151 0.75 SELL (0.58) THRBSELLSELPCYP3A4AKR1C4
SCHEMBL32667930 0.74 SELL (0.52) THRBSELLSELPCYP3A4AKR1C4
SCHEMBL28610455 0.73 SELL (0.56) THRBSELLSELPCYP3A4AKR1C4
SCHEMBL29949069 0.73 CYP3A4 (0.45) THRBSELLSELPCYP3A4ACHE
SCHEMBL19284449 0.73 CYP3A4 (0.45) THRBSELLSELPCYP3A4ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113363483-A Olivine-structure positive electrode material, preparation method and application thereof, and lithium ion battery 北京当升材料科技股份有限公司 2021-09-07 CN disclosed