Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.69 |
| ▸ | ESR1 | P03372 | 3/20 | 0.69 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.58 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27989541 | 0.94 | ESR2 (0.62) | ESR2ESR1HSD17B1HSD17B2CYP17A1 | |
| SCHEMBL3811825 | 0.87 | HSD17B1 (0.72) | ESR2ESR1HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL13589555 | 0.87 | HSD17B1 (0.72) | ESR2ESR1HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL25804086 | 0.86 | HSD17B1 (0.56) | ESR2ESR1HSD17B1HSD17B2CYP17A1 | |
| SCHEMBL27849732 | 0.85 | HSD17B1 (0.61) | ESR2ESR1HSD17B1HSD17B2CYP17A1 | |
| SCHEMBL29429121 | 0.84 | HSD17B1 (0.68) | ESR2ESR1HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL272034 | 0.84 | HSD17B1 (0.68) | ESR2ESR1HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL29696046 | 0.84 | HSD17B1 (0.68) | ESR2ESR1HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL26979937 | 0.84 | HSD17B1 (0.68) | ESR2ESR1HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL2941544 | 0.82 | MCL1 (0.61) | ESR2ESR1HSD17B1HSD17B2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713449-B2 | Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell | TORAY INDUSTRIES, INC. (JP) | 2010-05-11 | — | — | US | disclosed |
| US-20060180796-A1 | Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell | TORAY INDUSTRIES, INC. (JP) | 2006-08-17 | — | — | US | disclosed |
| EP-1619735-A1 | POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL | TORAY INDUSTRIES, INC. (JP) | 2006-01-25 | — | — | EP | disclosed |