SCHEMBL2862217

SCHEMBL2862217

COC(C[C@H](N)C(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.54
SLC1A1 P43005 9/20 0.48
SLC1A2 P43004 8/20 0.48
SLC1A3 P43003 7/20 0.48
GRIK1 P39086 6/20 0.45
GRIK2 Q13002 5/20 0.45
GGT1 P19440 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25564416 0.82 SLC7A5 (0.43) SLC7A5SLC1A1SLC1A2SLC1A3
SCHEMBL3187052 0.79 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A2SLC1A3GRIK1
SCHEMBL25660521 0.77 SLC7A5 (0.60) SLC7A5SLC1A1SLC1A2SLC1A3GRIK1
Leucine SCHEMBL6450505 0.77 SLC7A5 (0.82) SLC7A5SLC1A1SLC1A2SLC1A3GRIK1
SCHEMBL16584647 0.77 SLC7A5 (0.60) SLC7A5SLC1A1SLC1A2SLC1A3GRIK1
Hydrochloric Acid SCHEMBL8892666 0.77 SLC7A5 (0.65) SLC7A5SLC1A1SLC1A2SLC1A3GRIK1
SCHEMBL4961345 0.77 SLC7A5 (0.48) SLC7A5SLC1A1SLC1A2SLC1A3GRIK1
SCHEMBL13461523 0.76 LAP3 (0.48) SLC7A5SLC1A2SLC1A3
SCHEMBL14445462 0.76 SLC1A3 (0.34) SLC7A5SLC1A1SLC1A2SLC1A3
SCHEMBL8072286 0.76 LAP3 (0.48) SLC7A5SLC1A2SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2143728-A1 Improved process for the preparation of copolymer-1 Momenta Pharmaceuticals, Inc. (US) 2010-01-13 EP disclosed
EP-2046817-B1 IMPROVED PROCESS FOR THE PREPARATION OF COPOLYMER-1 MOMENTA PHARMACEUTICALS INC (US) 2009-12-16 EP disclosed
EP-2046817-A1 IMPROVED PROCESS FOR THE PREPARATION OF COPOLYMER-1 Momenta Pharmaceuticals, Inc. (US) 2009-04-15 EP disclosed
US-20080021192-A1 PROCESS FOR THE PREPARATION OF COPOLYMER-1 MOMENTA PHARMACEUTICALS, INC. (US) 2008-01-24 US disclosed
WO-2008006026-A1 IMPROVED PROCESS FOR THE PREPARATION OF COPOLYMER-1 MOMENTA PHARMACEUTICALS, INC. (US) 2008-01-10 WO disclosed
CN-1052144-A The Compounds and methods for of diagnosis and treatment cancer AUSTRALIAN COMMERCIAL RESEARCH (AU) 1991-06-12 CN disclosed