Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | PKM | P14618 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18432518 | 0.82 | LMNA (0.31) | LMNA | |
| SCHEMBL3379260 | 0.81 | LMNA (0.53) | LMNAMAPTPKMCYP1A2CYP2D6 | |
| SCHEMBL11407964 | 0.80 | LMNA (0.42) | LMNAMAPTPKMCYP1A2CYP2D6 | |
| SCHEMBL28149229 | 0.79 | MAPT (0.39) | LMNAMAPTPKMCYP1A2CYP2D6 | |
| SCHEMBL5386070 | 0.77 | KDM4E (0.48) | LMNAMAPTPKMCYP1A2CYP2D6 | |
| SCHEMBL214157 | 0.77 | LMNA (0.68) | LMNAMAPTPKMCYP1A2CYP2D6 | |
| SCHEMBL29872559 | 0.77 | LMNA (0.68) | LMNAMAPTPKMCYP1A2CYP2D6 | |
| SCHEMBL1245089 | 0.74 | LMNA (0.65) | LMNAMAPTPKMCYP1A2CYP2D6 | |
| SCHEMBL69082 | 0.74 | LMNA (0.65) | LMNAMAPTPKMCYP1A2CYP2D6 | |
| SCHEMBL9556365 | 0.74 | LMNA (0.65) | LMNAMAPTPKMCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248638-A | Phosphine metallocene catalyst, preparation method and application | 北京化工大学 | 2021-08-13 | — | — | CN | disclosed |