Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 17/20 | 0.51 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 7/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 7/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633462 | 0.91 | FGFR1 (0.59) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL19633583 | 0.90 | FGFR1 (0.59) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL28611756 | 0.86 | FGFR1 (0.37) | FGFR1FGFR4FGFR2FGFR3EGFR | |
| SCHEMBL20836816 | 0.86 | FGFR1 (0.58) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL20836824 | 0.85 | FGFR1 (0.55) | FGFR1FGFR4FGFR2FGFR3EGFR | |
| SCHEMBL19633338 | 0.84 | FGFR1 (0.59) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL24158275 | 0.83 | FGFR1 (0.56) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL20836822 | 0.80 | FGFR1 (0.51) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL28610611 | 0.79 | FGFR1 (0.48) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL20836820 | 0.79 | FGFR1 (0.51) | FGFR1FGFR4FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107400092-B | Pyrimidine derivative, preparation method thereof and application thereof in medicine | 浙江海正药业股份有限公司 | 2021-08-24 | — | — | CN | disclosed |