Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23112144 | 0.88 | KDM4E (0.59) | KDM4EL3MBTL1TDP1SLC6A2SLC6A4 | |
| SCHEMBL1007504 | 0.86 | GRM2 (0.43) | KDM4EL3MBTL1TDP1SLC6A2SLC6A4 | |
| SCHEMBL27695068 | 0.83 | KDM4E (0.43) | KDM4EL3MBTL1TDP1SLC6A2SLC6A4 | |
| SCHEMBL22111020 | 0.83 | L3MBTL1 (0.60) | KDM4EL3MBTL1TDP1MEN1CYP1A2 | |
| SCHEMBL6002091 | 0.82 | L3MBTL1 (0.47) | KDM4EL3MBTL1TDP1SLC6A2SLC6A4 | |
| SCHEMBL6479626 | 0.82 | L3MBTL1 (0.42) | KDM4EL3MBTL1TDP1SLC6A2SLC6A4 | |
| SCHEMBL8216509 | 0.82 | L3MBTL1 (0.50) | KDM4EL3MBTL1TDP1SLC6A2SLC6A4 | |
| SCHEMBL5706786 | 0.82 | GRM2 (0.42) | KDM4EL3MBTL1TDP1SLC6A2SLC6A4 | |
| SCHEMBL4170381 | 0.82 | L3MBTL1 (0.42) | KDM4EL3MBTL1TDP1SLC6A2SLC6A4 | |
| SCHEMBL17393516 | 0.82 | SLC6A2 (0.44) | KDM4EL3MBTL1TDP1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109082281-B | Liquid crystal compound with negative dielectric anisotropy as well as preparation method and application thereof | 北京八亿时空液晶科技股份有限公司 | 2021-09-07 | — | — | CN | disclosed |