SCHEMBL28623010

SCHEMBL28623010

CCC=CCCCCc1cccc(C(=O)OC)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 3/20 0.43
BCL2L1 Q07817 3/20 0.43
MCL1 Q07820 3/20 0.43
BAK1 Q16611 3/20 0.43
F7 P08709 3/20 0.43
F3 P13726 3/20 0.43
MMP2 P08253 2/20 0.43
ALOX15 P16050 2/20 0.43
HSD17B10 Q99714 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
ECE1 P42892 1/20 0.43
SGMS1 Q86VZ5 1/20 0.43
SGMS2 Q8NHU3 1/20 0.43
MUS81 Q96NY9 1/20 0.43
SAE1 Q9UBE0 1/20 0.43
ALDH1A1 P00352 4/20 0.42
LMNA P02545 1/20 0.42
DHODH Q02127 1/20 0.40
EPHX2 P34913 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23748630 1.00 BID (0.43) BIDBCL2L1MCL1BAK1F7
SCHEMBL23748651 0.85 F7 (0.52) BIDBCL2L1MCL1BAK1F7
SCHEMBL28610783 0.85 F7 (0.52) BIDBCL2L1MCL1BAK1F7
SCHEMBL23748695 0.82 PPARA (0.51) BIDBCL2L1MCL1BAK1SAE1
SCHEMBL20476363 0.82 ALDH1A1 (0.49) BIDBCL2L1MCL1BAK1HSD17B10
SCHEMBL23748692 0.81 MAPT (0.44) ALOX15HSD17B10KDM4EMAPTALDH1A1
SCHEMBL28614075 0.81 MAPT (0.44) ALOX15HSD17B10KDM4EMAPTALDH1A1
SCHEMBL3366019 0.79 F7 (0.60) BIDBCL2L1MCL1BAK1F7
SCHEMBL7444828 0.77 ALDH1A1 (0.51) HSD17B10KDM4EMAPTALDH1A1LMNA
SCHEMBL3366021 0.77 F7 (0.68) BIDBCL2L1MCL1BAK1F7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166024-A Aromatic compounds and their medical use 巴斯夫股份公司 2021-07-23 CN disclosed