Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619628 | 0.85 | KDM4E (0.57) | KDM4ETSHRSMN1; SMN2ALOX15HTT | |
| SCHEMBL28920726 | 0.84 | KDM4E (0.56) | KDM4ETSHRSMN1; SMN2ALOX15HTT | |
| SCHEMBL28611606 | 0.82 | KDM4E (0.58) | KDM4ETSHRSMN1; SMN2ALOX15HTT | |
| SCHEMBL15619629 | 0.81 | KDM4E (0.76) | KDM4ETSHRSMN1; SMN2ALOX15HTT | |
| SCHEMBL28610828 | 0.81 | KDM4E (0.65) | KDM4ETSHRSMN1; SMN2ALOX15HTT | |
| SCHEMBL15619432 | 0.79 | KDM4E (0.76) | KDM4ETSHRSMN1; SMN2ALOX15HTT | |
| SCHEMBL15619540 | 0.78 | KDM4E (0.77) | KDM4ETSHRSMN1; SMN2ALOX15HTT | |
| SCHEMBL17079654 | 0.78 | KDM4E (1.00) | KDM4ETSHRSMN1; SMN2ALOX15HTT | |
| SCHEMBL15619476 | 0.77 | KDM4E (0.76) | KDM4ETSHRSMN1; SMN2ALOX15HTT | |
| SCHEMBL28611642 | 0.77 | KDM4E (0.54) | KDM4ETSHRSMN1; SMN2ALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301959-A | Substituted chromen-4-ones for the treatment and prevention of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2021-08-24 | — | — | CN | disclosed |