Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.76 |
| ▸ | TSHR | P16473 | 4/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.76 |
| ▸ | HTT | P42858 | 2/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.72 |
| ▸ | MEN1 | O00255 | 8/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 5/20 | 0.72 |
| ▸ | TP53 | P04637 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 1/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.62 |
| ▸ | TUBB | P07437 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17079654 | 0.86 | KDM4E (1.00) | KDM4ETSHRALOX15HTTSMN1; SMN2 | |
| SCHEMBL15619540 | 0.86 | KDM4E (0.77) | KDM4ETSHRALOX15HTTSMN1; SMN2 | |
| SCHEMBL15619629 | 0.85 | KDM4E (0.76) | KDM4ETSHRALOX15HTTSMN1; SMN2 | |
| SCHEMBL15619432 | 0.85 | KDM4E (0.76) | KDM4ETSHRALOX15HTTSMN1; SMN2 | |
| SCHEMBL21446879 | 0.84 | KDM4E (0.75) | KDM4ETSHRALOX15HTTSMN1; SMN2 | |
| SCHEMBL31675993 | 0.84 | KDM4E (1.00) | KDM4ETSHRALOX15HTTSMN1; SMN2 | |
| SCHEMBL4649481 | 0.84 | KDM4E (1.00) | KDM4ETSHRALOX15HTTSMN1; SMN2 | |
| SCHEMBL15619433 | 0.81 | KDM4E (0.70) | KDM4ETSHRALOX15HTTSMN1; SMN2 | |
| 3-Hydroxy-3',4'-Dimethoxyflavone SCHEMBL15676607 | 0.80 | KDM4E (1.00) | KDM4ETSHRALOX15HTTSMN1; SMN2 | |
| 3-Hydroxy-3',4'-Dimethoxyflavone SCHEMBL30139617 | 0.80 | KDM4E (1.00) | KDM4ETSHRALOX15HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9629822-B2 | Flavonoid based antiviral targets | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-20150209323-A1 | FLAVONOID BASED ANTIVIRAL TARGETS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, (US) | 2015-07-30 | — | — | US | disclosed |
| WO-2014047551-A1 | FLAVONOID BASED ANTIVIRAL TARGETS | UNIVERSITY OF CENTER FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150209323-A1 | FLAVONOID BASED ANTIVIRAL TARGETS | RBM28, MAVS, HAVCR2 | KDM4E 3580/4885TSHR 3813/4885ALOX15 3312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.