Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356331 | 0.95 | NAAA (0.58) | NAAAFAAHTSHRRAD52NPSR1 | |
| SCHEMBL6657722 | 0.95 | NAAA (0.58) | NAAAFAAHTSHRRAD52NPSR1 | |
| SCHEMBL3681702 | 0.95 | NAAA (0.58) | NAAAFAAHTSHRRAD52NPSR1 | |
| SCHEMBL2518200 | 0.95 | NAAA (0.58) | NAAAFAAHTSHRRAD52NPSR1 | |
| SCHEMBL3284153 | 0.95 | NAAA (0.58) | NAAAFAAHTSHRRAD52NPSR1 | |
| SCHEMBL6340150 | 0.95 | NAAA (0.58) | NAAAFAAHTSHRRAD52NPSR1 | |
| SCHEMBL6658555 | 0.95 | NAAA (0.58) | NAAAFAAHTSHRRAD52NPSR1 | |
| SCHEMBL2240975 | 0.95 | NAAA (0.58) | NAAAFAAHTSHRRAD52NPSR1 | |
| Itaconate SCHEMBL9244321 | 0.94 | TSHR (0.51) | NAAAFAAHTSHRRAD52NPSR1 | |
| SCHEMBL28441542 | 0.93 | NAAA (0.56) | NAAAFAAHTSHRRAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110507823-B | Application of itaconic acid related substance in diagnosis and prevention of virus infectious diseases | 中国医学科学院基础医学研究所 | 2021-08-24 | — | — | CN | disclosed |