Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 9/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 9/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614755 | 0.86 | CSNK2A2 (0.38) | CSNK2A2CSNK2BCSNK2A1ABCC1ABCG2 | |
| SCHEMBL28920734 | 0.86 | CSNK2A2 (0.47) | CSNK2A2CSNK2BCSNK2A1ABCC1ABCG2 | |
| SCHEMBL22230875 | 0.86 | CSNK2A2 (0.53) | CSNK2A2CSNK2BCSNK2A1ABCC1ABCG2 | |
| SCHEMBL22231391 | 0.82 | CSNK2A2 (0.41) | CSNK2A2CSNK2BCSNK2A1ABCC1ABCG2 | |
| SCHEMBL22231502 | 0.82 | TERT (0.50) | CSNK2A2CSNK2BCSNK2A1CYP1A1CYP1A2 | |
| SCHEMBL22245055 | 0.82 | CSNK2A2 (0.43) | CSNK2A2CSNK2BCSNK2A1ABCC1ABCG2 | |
| SCHEMBL28610230 | 0.81 | KDM4E (0.46) | CSNK2A2CSNK2BCSNK2A1ABCC1ABCG2 | |
| SCHEMBL28920731 | 0.80 | CYP1A1 (0.56) | CSNK2A2CSNK2BCSNK2A1ABCC1ABCG2 | |
| SCHEMBL22231445 | 0.79 | CSNK2A2 (0.39) | CSNK2A2CSNK2BCSNK2A1ABCC1ABCG2 | |
| SCHEMBL22231443 | 0.79 | CSNK2A2 (0.39) | CSNK2A2CSNK2BCSNK2A1ABCC1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301959-A | Substituted chromen-4-ones for the treatment and prevention of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2021-08-24 | — | — | CN | disclosed |