Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.44 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28623691 | 1.00 | PAM (0.49) | PAMHDAC1HDAC6KDM4EKMT2A | |
| SCHEMBL11883033 | 0.84 | PAM (0.53) | PAMKDM4EKMT2AMEN1LMNA | |
| SCHEMBL11883048 | 0.84 | PAM (0.53) | PAMKDM4EKMT2AMEN1LMNA | |
| SCHEMBL27965115 | 0.83 | PAM (0.52) | PAMHDAC1HDAC6KDM4EKMT2A | |
| SCHEMBL27965116 | 0.83 | PAM (0.52) | PAMHDAC1HDAC6KDM4EKMT2A | |
| SCHEMBL27964770 | 0.80 | PAM (0.49) | PAMKDM4EKMT2AMEN1LMNA | |
| SCHEMBL29129626 | 0.80 | PAM (0.49) | PAMHDAC1HDAC6KMT2AMEN1 | |
| SCHEMBL9469694 | 0.79 | KMT2A (0.50) | HDAC1HDAC6KMT2AMEN1ACHE | |
| SCHEMBL28616636 | 0.78 | NR1I2 (0.54) | PAMKMT2AMEN1CYP1B1LMNA | |
| SCHEMBL28616637 | 0.78 | NR1I2 (0.54) | PAMKMT2AMEN1CYP1B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113277963-A | Amine compound and preparation method and application thereof | 南京工业大学 | 2021-08-20 | — | — | CN | claimed |
| CN-118373763-A | Allylamine compound and preparation method thereof | 华中师范大学 | 2024-07-23 | — | — | CN | disclosed |
| CN-113277963-B | Amine compound and preparation method and application thereof | 南京工业大学 | 2022-11-04 | — | — | CN | disclosed |
| CN-113277963-A | Amine compound and preparation method and application thereof | 南京工业大学 | 2021-08-20 | — | — | CN | disclosed |