Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 9/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28616979 | 0.80 | FABP3 (0.46) | RXFP1ALDH1A1KDM4EFABP3FABP4 | |
| SCHEMBL28607526 | 0.80 | ALDH1A1 (0.58) | MAPTALDH1A1POLBLMNA | |
| SCHEMBL3391977 | 0.78 | MAPT (0.47) | RXFP1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL28920604 | 0.78 | HTR2C (0.42) | MAPTALDH1A1KDM4EFABP3FABP4 | |
| SCHEMBL28616980 | 0.77 | POLB (0.50) | MAPTALDH1A1POLBLMNATP53 | |
| SCHEMBL28615045 | 0.77 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL28921066 | 0.77 | ALDH1A1 (0.52) | MAPTALDH1A1POLBFABP3FABP4 | |
| SCHEMBL29528197 | 0.77 | KDM4E (0.43) | RXFP1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL19423236 | 0.76 | FABP3 (0.65) | RXFP1MAPTFABP3FABP4LMNA | |
| SCHEMBL28616976 | 0.74 | SMN1; SMN2 (0.62) | MAPTALDH1A1KDM4EPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248438-A | Pyrazole compound and preparation method thereof | 浙大城市学院 | 2021-08-13 | — | — | CN | claimed |
| CN-113248438-B | Pyrazole compound and preparation method thereof | 浙大城市学院 | 2022-04-12 | — | — | CN | disclosed |
| CN-113248438-A | Pyrazole compound and preparation method thereof | 浙大城市学院 | 2021-08-13 | — | — | CN | disclosed |