Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 10/20 | 0.42 |
| ▸ | TEC | P42680 | 9/20 | 0.42 |
| ▸ | TXK | P42681 | 9/20 | 0.42 |
| ▸ | BMX | P51813 | 9/20 | 0.42 |
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
| ▸ | ITK | Q08881 | 4/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 4/20 | 0.38 |
| ▸ | RET | P07949 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14636369 | 1.00 | BTK (0.42) | BTKTECTXKBMXEGFR | |
| SCHEMBL20550584 | 0.81 | ATM (0.47) | BTKTNK2 | |
| SCHEMBL18849915 | 0.81 | ATM (0.47) | BTKTNK2 | |
| SCHEMBL14636998 | 0.80 | BTK (0.41) | BTKTECTXKBMXEGFR | |
| SCHEMBL18099733 | 0.80 | ABL1 (0.53) | BTKTNK2RETKDRABL1 | |
| SCHEMBL18849914 | 0.78 | ABL1 (0.43) | BTKTNK2RETKDRABL1 | |
| SCHEMBL18849916 | 0.78 | ABL1 (0.43) | BTKTNK2RETKDRABL1 | |
| SCHEMBL17800128 | 0.78 | BTK (0.38) | BTKTECTXKBMXEGFR | |
| SCHEMBL17800127 | 0.78 | BTK (0.38) | BTKTECTXKBMXEGFR | |
| SCHEMBL14637032 | 0.74 | BTK (0.41) | BTKEGFRTNK2RETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602827-B | Imidazopyrazine inhibitors of Bruton's tyrosine kinase | 安塞塔制药公司 | 2021-08-20 | — | — | CN | disclosed |