Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23826972 | 1.00 | USP2 (0.42) | USP2SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL23826974 | 1.00 | USP2 (0.42) | USP2SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL29482377 | 1.00 | USP2 (0.42) | USP2SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL28804351 | 0.79 | USP2 (0.39) | USP2SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL28804350 | 0.79 | USP2 (0.39) | USP2SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL29715682 | 0.79 | USP2 (0.39) | USP2SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL12174992 | 0.79 | USP2 (0.51) | USP2SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL20571388 | 0.78 | USP2 (0.40) | USP2SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL20571390 | 0.78 | USP2 (0.40) | USP2SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL20571387 | 0.78 | USP2 (0.40) | USP2SMN1; SMN2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109475531-B | Heterocyclic inhibitors of PTPN11 | 得克萨斯州立大学董事会 | 2021-08-17 | — | — | CN | disclosed |