Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28804350 | 1.00 | USP2 (0.39) | USP2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL29715682 | 1.00 | USP2 (0.39) | USP2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL22799231 | 0.85 | — | — | |
| SCHEMBL22799234 | 0.85 | — | — | |
| SCHEMBL22799232 | 0.85 | — | — | |
| SCHEMBL23826974 | 0.79 | USP2 (0.42) | USP2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL23826972 | 0.79 | USP2 (0.42) | USP2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL29482377 | 0.79 | USP2 (0.42) | USP2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL28624038 | 0.79 | USP2 (0.42) | USP2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL22814430 | 0.77 | USP2 (0.46) | USP2SMN1; SMN2MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448923-B | Pyrimidine-fused ring compound, preparation method and application thereof | 上海青煜医药科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-110156786-B | Pyrimido-cyclic compounds, process for their preparation and their use | 青煜医药研发(上海)有限公司 | 2022-06-03 | — | — | CN | disclosed |