SCHEMBL2862470

SCHEMBL2862470

CCc1c(O)cc(C(=O)c2ccccc2)c(O)c1CC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.49
LMNA P02545 3/20 0.49
KDM4E B2RXH2 3/20 0.49
MAPT P10636 3/20 0.49
HSD17B10 Q99714 2/20 0.49
BCL2 P10415 1/20 0.49
MCL1 Q07820 1/20 0.49
CYP3A4 P08684 1/20 0.49
RECQL P46063 1/20 0.49
MEN1 O00255 1/20 0.47
USP2 O75604 1/20 0.47
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.47
KEAP1 Q14145 1/20 0.47
NFE2L2 Q16236 1/20 0.47
MAPK1 P28482 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HTT P42858 2/20 0.45
CYP1A2 P05177 1/20 0.45
PGR P06401 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28132998 0.92 BCL2 (0.54) HPGDLMNAKDM4EMAPTHSD17B10
SCHEMBL2866678 0.85 MEN1 (0.53) HPGDLMNAKDM4EMAPTHSD17B10
SCHEMBL2868258 0.84 HPGD (0.47) HPGDLMNAKDM4EMAPTHSD17B10
SCHEMBL2861278 0.84 BCL2 (0.53) HPGDLMNAKDM4EMAPTHSD17B10
SCHEMBL5672203 0.79 BCL2 (0.53) HPGDLMNAKDM4EMAPTHSD17B10
SCHEMBL1446427 0.79 BCL2 (0.50) HPGDLMNAKDM4EMAPTHSD17B10
SCHEMBL11102516 0.78 HPGD (0.53) HPGDLMNAKDM4EMAPTHSD17B10
SCHEMBL27589610 0.77 BCL2 (0.56) HPGDLMNAKDM4EMAPTHSD17B10
SCHEMBL5477374 0.77 KAT8 (0.48) HPGDLMNAKDM4EMAPTHSD17B10
SCHEMBL27607231 0.77 KAT8 (0.48) HPGDLMNAKDM4EMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed