Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624781 | 1.00 | KAT2B (0.37) | KAT2BAXLHRH4 | |
| SCHEMBL21386121 | 0.89 | KAT2B (0.47) | KAT2B | |
| SCHEMBL21386122 | 0.89 | KAT2B (0.47) | KAT2B | |
| SCHEMBL15806909 | 0.88 | LRRK2 (0.31) | KAT2B | |
| SCHEMBL21386066 | 0.83 | HRH4 (0.34) | HRH4 | |
| SCHEMBL1180390 | 0.83 | EHMT2 (0.35) | — | |
| SCHEMBL28621310 | 0.82 | ALDH1A1 (0.33) | HRH4 | |
| SCHEMBL28621312 | 0.82 | ALDH1A1 (0.33) | HRH4 | |
| SCHEMBL28632204 | 0.82 | ALDH1A1 (0.33) | HRH4 | |
| SCHEMBL1179409 | 0.79 | CHRM2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897038-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维爱尔兰无限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-108175749-B | Melt-extruded solid dispersions containing apoptosis-inducing agents | 艾伯维爱尔兰无限公司 | 2021-09-10 | — | — | CN | disclosed |