Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.51 |
| ▸ | GNPAT | O15228 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31374694 | 0.85 | ECE1 (0.46) | GNPATACEMMP1MMP3 | |
| SCHEMBL31374730 | 0.83 | AKT1 (0.52) | AKT1GNPATRENACEMMP1 | |
| SCHEMBL28620366 | 0.83 | AKT1 (0.52) | AKT1GNPATRENACEMMP1 | |
| SCHEMBL31374735 | 0.80 | FOLH1 (0.55) | MMP9 | |
| SCHEMBL28620270 | 0.77 | AKT1 (0.55) | AKT1GNPATMMP1MMP3MMP9 | |
| SCHEMBL28620268 | 0.77 | AKT1 (0.55) | AKT1GNPATMMP1MMP3MMP9 | |
| SCHEMBL29309809 | 0.77 | AKT1 (0.69) | AKT1RENACECTSSCTSL | |
| SCHEMBL22207325 | 0.76 | AKT1 (0.69) | AKT1RENACEMMP1MMP3 | |
| SCHEMBL22207323 | 0.76 | AKT1 (0.69) | AKT1RENACEMMP1MMP3 | |
| SCHEMBL31374698 | 0.76 | AKT1 (0.39) | AKT1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301920-A | Complexes comprising ligands, spacers, peptide linkers and biomolecules | 安斯泰来制药株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-113271973-A | Complex comprising a ligand and a CEACAM5 antibody Fab fragment | 安斯泰来制药株式会社 | 2021-08-17 | — | — | CN | disclosed |