Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 4/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28620922 | 1.00 | AKT1 (0.39) | AKT1FOLH1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL28620366 | 0.90 | AKT1 (0.52) | AKT1ACE | |
| SCHEMBL31374730 | 0.90 | AKT1 (0.52) | AKT1ACE | |
| SCHEMBL29333170 | 0.81 | AKT1 (0.55) | AKT1PTGS1PTGS2ALDH1A1TSHR | |
| SCHEMBL23113662 | 0.80 | AKT1 (0.48) | AKT1FOLH1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL28620371 | 0.76 | FOLH1 (0.41) | AKT1FOLH1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL28624841 | 0.76 | AKT1 (0.51) | AKT1ACE | |
| SCHEMBL22044586 | 0.76 | AKT1 (0.48) | AKT1FOLH1ALDH1A1TSHRMAPT | |
| SCHEMBL31235812 | 0.75 | AKT1 (0.42) | AKT1FOLH1PTGS1PTGS2ACE | |
| SCHEMBL28620369 | 0.74 | AKT1 (0.41) | AKT1PTGS1PTGS2ALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301920-B | Complexes comprising a ligand, a spacer, a peptide linker and a biomolecule | 安斯泰来制药株式会社 | 2025-01-14 | — | — | CN | disclosed |