Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4527107 | 0.85 | ALDH1A1 (0.64) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL5089650 | 0.84 | JAK2 (0.52) | TSHRALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL5975125 | 0.80 | ALDH1A1 (0.74) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL5975366 | 0.80 | ALDH1A1 (0.74) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL5893357 | 0.79 | TSHR (0.73) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| Biphenyl SCHEMBL27403396 | 0.79 | ALDH1A1 (0.87) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL9587934 | 0.78 | ALDH1A1 (0.61) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL6399746 | 0.78 | ALDH1A1 (0.65) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL21056612 | 0.77 | NR4A2 (0.56) | ALDH1A1MAPT | |
| Biphenyl SCHEMBL28278261 | 0.77 | ALDH1A1 (0.84) | TSHRALDH1A1LMNAMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113395965-A | USP19 inhibitors for treatment | 阿尔麦克探索有限公司 | 2021-09-14 | — | — | CN | claimed |
| CN-113395965-A | USP19 inhibitors for treatment | 阿尔麦克探索有限公司 | 2021-09-14 | — | — | CN | disclosed |