Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22207234 | 0.86 | AKT1 (0.45) | AKT1KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL22207235 | 0.86 | AKT1 (0.45) | AKT1KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL22207315 | 0.86 | FNTA (0.50) | AKT1CA2KDM4EMAPTPOLB | |
| SCHEMBL22207314 | 0.86 | FNTA (0.50) | AKT1CA2KDM4EMAPTPOLB | |
| SCHEMBL28619772 | 0.84 | FNTA (0.46) | AKT1CA2F10 | |
| SCHEMBL18942764 | 0.79 | AKT1 (0.52) | CTSSCTSKAKT1ALDH1A1HPGD | |
| SCHEMBL29309809 | 0.78 | AKT1 (0.69) | CTSSCTSKAKT1 | |
| SCHEMBL22297607 | 0.78 | BACE1 (0.48) | CTSSCTSKAKT1BACE1 | |
| SCHEMBL23113662 | 0.78 | AKT1 (0.48) | CTSSCTSKAKT1ALDH1A1HDAC4 | |
| SCHEMBL29460392 | 0.78 | KLK7 (0.56) | CTSSCTSKKLK7KLK5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301920-A | Complexes comprising ligands, spacers, peptide linkers and biomolecules | 安斯泰来制药株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-113271973-A | Complex comprising a ligand and a CEACAM5 antibody Fab fragment | 安斯泰来制药株式会社 | 2021-08-17 | — | — | CN | disclosed |