Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 17/20 | 0.37 |
| ▸ | HTR2C | P28335 | 16/20 | 0.37 |
| ▸ | HTR2A | P28223 | 13/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28642097 | 0.89 | PARP1 (0.36) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30351742 | 0.79 | PARP1 (0.38) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL21008766 | 0.77 | PARP1 (0.49) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL16382727 | 0.77 | PARP1 (0.49) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| Hydrochloric Acid SCHEMBL16334754 | 0.76 | PARP1 (0.48) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| Hydrochloric Acid SCHEMBL16337337 | 0.76 | PARP1 (0.48) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30352171 | 0.76 | PARP1 (0.38) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30351948 | 0.75 | PARP1 (0.37) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30351930 | 0.75 | PARP1 (0.37) | PARP1HTR2BHTR2CHTR3EHTR3B | |
| SCHEMBL28625447 | 0.74 | HTR2C (0.37) | PARP1HTR2BHTR2CHTR2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423701-A | Substituted isoindolinones | 拜欧斯瑞克斯公司 | 2021-09-21 | — | — | CN | disclosed |