Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 17/20 | 0.37 |
| ▸ | HTR2B | P41595 | 17/20 | 0.37 |
| ▸ | HTR2A | P28223 | 12/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21932889 | 0.77 | — | — | |
| SCHEMBL21932896 | 0.75 | IKZF2 (0.42) | — | |
| SCHEMBL21932917 | 0.74 | CRBN (0.52) | — | |
| SCHEMBL28625341 | 0.74 | PARP1 (0.40) | HTR2CHTR2BHTR2APARP1MAPK1 | |
| SCHEMBL21932888 | 0.74 | IKZF2 (0.33) | — | |
| SCHEMBL23703765 | 0.74 | CRBN (0.47) | — | |
| SCHEMBL30351742 | 0.74 | PARP1 (0.38) | HTR2CHTR2BHTR2APARP1MAPK1 | |
| SCHEMBL22000761 | 0.74 | CRBN (0.51) | — | |
| SCHEMBL22001054 | 0.74 | CRBN (0.32) | — | |
| SCHEMBL22000914 | 0.74 | CRBN (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423701-A | Substituted isoindolinones | 拜欧斯瑞克斯公司 | 2021-09-21 | — | — | CN | disclosed |