Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.50 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | KDM6A | O15550 | 1/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | KDM4B | O94953 | 1/20 | 0.50 |
| ▸ | KDM5C | P41229 | 1/20 | 0.50 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.50 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955977 | 0.82 | KDM4E (0.59) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A | |
| SCHEMBL2842427 | 0.79 | KDM4E (0.68) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A | |
| SCHEMBL824860 | 0.79 | ESR1 (0.54) | NPC1RAB9ANPSR1IDO1MEN1 | |
| SCHEMBL27713924 | 0.78 | KDM4E (0.67) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A | |
| SCHEMBL7531777 | 0.77 | COMT (0.54) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A | |
| SCHEMBL8031376 | 0.77 | KDM4E (0.60) | KDM4EL3MBTL1NPC1RAB9ANPSR1 | |
| SCHEMBL28624547 | 0.77 | FABP5 (0.46) | KDM4EL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL10720203 | 0.76 | TYMS (0.56) | KDM4EL3MBTL1NPC1RAB9ANPSR1 | |
| SCHEMBL11852768 | 0.76 | KDM4E (0.43) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A | |
| SCHEMBL4205753 | 0.75 | LMNA (0.64) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354666-A | Four kinds of D-A' - (Pi-A)2Type polymeric salicylaldehyde Schiff base derivative metal complex and preparation method and application thereof | 湘潭大学 | 2021-09-07 | — | — | CN | disclosed |