Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.71 |
| ▸ | KDM4A | O75164 | 3/20 | 0.71 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.71 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.71 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.71 |
| ▸ | KDM6B | O15054 | 1/20 | 0.71 |
| ▸ | KDM6A | O15550 | 1/20 | 0.71 |
| ▸ | TET3 | O43151 | 1/20 | 0.71 |
| ▸ | KDM4B | O94953 | 1/20 | 0.71 |
| ▸ | KDM5C | P41229 | 1/20 | 0.71 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.71 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.71 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.71 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.71 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.71 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.71 |
| ▸ | COMT | P21964 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068195 | 0.83 | KDM4E (1.00) | KDM4EL3MBTL1KDM4AEGLN1KDM4C | |
| SCHEMBL29349767 | 0.83 | KDM4E (1.00) | KDM4EL3MBTL1KDM4AEGLN1KDM4C | |
| SCHEMBL14618449 | 0.82 | KDM4E (0.67) | KDM4EL3MBTL1KDM4AEGLN1KDM4C | |
| SCHEMBL27468637 | 0.82 | KDM4E (0.77) | KDM4EL3MBTL1KDM4AEGLN1KDM4C | |
| SCHEMBL7646199 | 0.79 | KDM4E (1.00) | KDM4EL3MBTL1KDM4AEGLN1KDM4C | |
| SCHEMBL163474 | 0.79 | KDM4E (0.73) | KDM4EL3MBTL1KDM4AEGLN1KDM4C | |
| SCHEMBL29462403 | 0.79 | KDM4E (0.73) | KDM4EL3MBTL1KDM4AEGLN1KDM4C | |
| SCHEMBL10582092 | 0.78 | COMT (0.76) | KDM4EL3MBTL1KDM4AEGLN1KDM4C | |
| SCHEMBL27713924 | 0.78 | KDM4E (0.67) | KDM4EL3MBTL1KDM4AEGLN1KDM4C | |
| SCHEMBL22604619 | 0.78 | KDM4E (0.58) | KDM4EL3MBTL1KDM4AEGLN1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354666-A | Four kinds of D-A' - (Pi-A)2Type polymeric salicylaldehyde Schiff base derivative metal complex and preparation method and application thereof | 湘潭大学 | 2021-09-07 | — | — | CN | disclosed |